Induction of sirtuin-1 signaling by resveratrol induces human chondrosarcoma cell apoptosis and exhibits antitumor activity
Chondrosarcoma is a malignant primary bone tumor. Sirtuin-1 (SIRT1), which is a member
of sirtuin family, plays a dual role either in cancer promotion or suppression. There is no
report about the role of SIRT1 in the human chondrosarcoma cells. Resveratrol is a potent
activator of SIRT1. However, its effects on chondrosarcoma have not been extensively
studied. Here, we investigated the role of SIRT1 induction by resveratrol in human
chondrosarcoma cell growth and tumor progression. Resveratrol significantly decreased cell …
of sirtuin family, plays a dual role either in cancer promotion or suppression. There is no
report about the role of SIRT1 in the human chondrosarcoma cells. Resveratrol is a potent
activator of SIRT1. However, its effects on chondrosarcoma have not been extensively
studied. Here, we investigated the role of SIRT1 induction by resveratrol in human
chondrosarcoma cell growth and tumor progression. Resveratrol significantly decreased cell …
Induction of sirtuin-1 signaling by resveratrol induces human chondrosarcoma cell apoptosis and exhibits antitumor activity.
CSC Chao SungChuan, CYJ Chen YingJu… - 2017 - cabidigitallibrary.org
Chondrosarcoma is a malignant primary bone tumor. Sirtuin-1 (SIRT1), which is a member
of sirtuin family, plays a dual role either in cancer promotion or suppression. There is no
report about the role of SIRT1 in the human chondrosarcoma cells. Resveratrol is a potent
activator of SIRT1. However, its effects on chondrosarcoma have not been extensively
studied. Here, we investigated the role of SIRT1 induction by resveratrol in human
chondrosarcoma cell growth and tumor progression. Resveratrol significantly decreased cell …
of sirtuin family, plays a dual role either in cancer promotion or suppression. There is no
report about the role of SIRT1 in the human chondrosarcoma cells. Resveratrol is a potent
activator of SIRT1. However, its effects on chondrosarcoma have not been extensively
studied. Here, we investigated the role of SIRT1 induction by resveratrol in human
chondrosarcoma cell growth and tumor progression. Resveratrol significantly decreased cell …
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